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Epithalon

CAS: 307297-39-8

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SKU:Epithalon

Epithalon is a synthetic tetrapeptide investigated in laboratory research for its role in telomerase-associated signaling, chromosomal stability mechanisms, and cellular aging-related pathways in controlled experimental models.

Epithalon
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Current Lot ID
2602-C110-10-001
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Scientific Context & Applications

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Scientific Context
Molecular classification and background.
Epithalon (Ala-Glu-Asp-Gly) is a synthetic peptide modeled after the pineal extract Epithalamin. In laboratory research systems, Epithalon has been examined for its interaction with telomerase-associated transcriptional mechanisms and circadian-linked cellular regulation. Research investigations have evaluated Epithalon for its involvement in:
  • Telomerase-associated gene expression regulation
  • Telomere length maintenance in replicative cell models
  • Pineal-linked circadian signaling pathways
  • Cellular senescence and lifespan-associated signaling mechanisms
All findings are derived from controlled non-clinical experimental systems and interpreted strictly at the molecular and cellular research level.

Laboratory Applications
Experimental models and settings.
  • Senescence Assays: Used in human fibroblast cultures to measure extension of the Hayflick limit.
  • Lifespan Studies: Investigated in Drosophila and rodent models for effects on maximum and mean lifespan.
  • Tumor Incidence: Applied in aging models to study the frequency of spontaneous tumor formation.
  • Circadian Regulation: Researched for effects on melatonin secretion patterns in pinealocyte cultures.

Scientific References
Peer-reviewed literature data.
  • Khavinson VH. (Khavinson VH.).“Peptides and Ageing.”Neuroendocrinology Letters
  • Anisimov VN, et al. (Anisimov VN, et al.).“Epithalon and longevity.”Experimental Gerontology
  • Khavinson VH, et al. (Khavinson VH, et al.).“Epithalon peptide induces telomerase activity.”Biogerontology
  • Anisimov VN, et al. (Anisimov VN, et al.).“Melatonin and epithalon.”Neuroendocrinology Letters
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