All Categories, Longevity & Cellular Research

Epithalon

CAS: 307297-39-8

SKU:Epithalon

Epithalon is a synthetic tetrapeptide investigated in laboratory research for its role in telomerase-associated signaling, chromosomal stability mechanisms, and cellular aging-related pathways in controlled experimental models.

Current Lot ID

2602-C110-10-001

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Scientific Context & Applications

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View extended technical data, molecular targets, signaling pathways, and historical research timelines for Epithalon

Scientific Context

Molecular classification and background.

Epithalon (Ala-Glu-Asp-Gly) is a synthetic peptide modeled after the pineal extract Epithalamin. In laboratory research systems, Epithalon has been examined for its interaction with telomerase-associated transcriptional mechanisms and circadian-linked cellular regulation. Research investigations have evaluated Epithalon for its involvement in:

Telomerase-associated gene expression regulation
Telomere length maintenance in replicative cell models
Pineal-linked circadian signaling pathways
Cellular senescence and lifespan-associated signaling mechanisms

All findings are derived from controlled non-clinical experimental systems and interpreted strictly at the molecular and cellular research level.

Laboratory Applications

Experimental models and settings.

Senescence Assays: Used in human fibroblast cultures to measure extension of the Hayflick limit.
Lifespan Studies: Investigated in Drosophila and rodent models for effects on maximum and mean lifespan.
Tumor Incidence: Applied in aging models to study the frequency of spontaneous tumor formation.
Circadian Regulation: Researched for effects on melatonin secretion patterns in pinealocyte cultures.

Scientific References

Peer-reviewed literature data.

Khavinson VH. (Khavinson VH.).“Peptides and Ageing.”Neuroendocrinology Letters
Anisimov VN, et al. (Anisimov VN, et al.).“Epithalon and longevity.”Experimental Gerontology
Khavinson VH, et al. (Khavinson VH, et al.).“Epithalon peptide induces telomerase activity.”Biogerontology
Anisimov VN, et al. (Anisimov VN, et al.).“Melatonin and epithalon.”Neuroendocrinology Letters

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Epithalon

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