All Categories, Longevity & Cellular Research

SS-31

CAS: 736992-21-5

SKU:SS-31

SS-31 is a mitochondria-targeted tetrapeptide investigated in laboratory research for its role in mitochondrial membrane stabilization, oxidative stress signaling, and bioenergetic regulation in controlled experimental models.

Current Lot ID

2602-C109-10-001, 2602-C109-50-001

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This product is intended for research purposes only.

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Technical Specification

Scientific Context & Applications

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View extended technical data, molecular targets, signaling pathways, and historical research timelines for SS-31

Scientific Context

Molecular classification and background.

Overview of molecular classification and research background. SS-31 is a synthetic, cell-permeable tetrapeptide characterized for its selective interaction with cardiolipin within the inner mitochondrial membrane. In laboratory research systems, SS-31 has been examined for its ability to stabilize mitochondrial membrane architecture and modulate oxidative signaling pathways. Experimental investigations have evaluated SS-31 for its involvement in:

Cardiolipin-associated mitochondrial membrane stabilization
Electron transport chain efficiency and bioenergetic regulation
Reactive oxygen species (ROS)–related signaling dynamics
Mitochondrial structural integrity under oxidative stress conditions

All observations are derived from controlled non-clinical experimental systems and interpreted strictly at the molecular and cellular research level.

Laboratory Applications

Experimental models and settings.

Experimental models and investigational settings.

Ischemia-Reperfusion Models: Utilized in laboratory systems examining mitochondrial integrity during oxidative stress conditions.
Cardiac Bioenergetics Research: Applied in experimental models evaluating mitochondrial-associated energetic signaling.
Neurodegenerative Signaling Studies: Investigated in in-vitro systems examining mitochondrial stress responses in neuronal cells.
Aging-Associated Mitochondrial Models: Used in research evaluating mitochondrial coupling efficiency and oxidative signaling markers.

All applications are limited to non-clinical research environments.

Scientific References

Peer-reviewed literature data.

Szeto HH. (Szeto HH.).“Mitochondria-targeted peptide antioxidants.”Antioxidants & Redox Signaling
Birk AV, et al. (Birk AV, et al.).“SS-31 and mitochondria.”Am. J. Physiol. Regul. Integr. Comp. Physiol.
Dai DF, et al. (Dai DF, et al.).“SS-31 in heart failure models.”Circulation: Heart Failure
Reddy PH, et al. (Reddy PH, et al.).“SS-31 in Alzheimer’s models.”Human Molecular Genetics

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Research Use Only

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Scientific Context & Applications

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