All Categories, Longevity & Cellular Research

NAD+ Buffered

CAS: 53-84-9

SKU:NAD+ Buffered

NAD+ Buffered is a laboratory-grade formulation of Nicotinamide Adenine Dinucleotide investigated in controlled research environments for its role in cellular redox balance, metabolic signaling, and NAD+-dependent enzymatic pathways.

Current Lot ID

2602-C114-500-001

Third-party analytical validation via HPLC & MS / Sequence matching verified

Research Use Only

This product is intended for research purposes only.

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Technical Specification

Scientific Context & Applications

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View extended technical data, molecular targets, signaling pathways, and historical research timelines for NAD+ Buffered

Scientific Context

Molecular classification and background.

Nicotinamide Adenine Dinucleotide (NAD⁺) is an essential intracellular coenzyme central to cellular energy metabolism and redox homeostasis. In laboratory research models, NAD⁺ functions as an electron carrier in oxidation–reduction reactions and serves as a substrate for multiple NAD⁺-dependent enzyme families. Experimental investigations have examined NAD⁺ for its involvement in:

Sirtuin-associated deacetylation and transcriptional regulation
Poly(ADP-ribose) polymerase (PARP)–mediated DNA repair signaling
CD38-related NAD⁺ turnover and calcium-associated signaling
Mitochondrial function and metabolic flux regulation

All observations are derived from controlled non-clinical experimental systems and interpreted strictly at the molecular and cellular research level.

Laboratory Applications

Experimental models and settings.

Experimental models and investigational settings.

Sirtuin Activity Assays: Utilized in cell-based systems to examine NAD⁺-dependent deacetylase signaling pathways.
Genotoxic Stress Models: Applied in laboratory environments evaluating PARP-associated DNA repair mechanisms.
Neuronal Signaling Research: Investigated in in-vitro models examining axonal integrity and NAD⁺-linked stress responses.
Metabolic Pathway Mapping: Used in isotope-tracing studies to assess NAD⁺ biosynthesis and recycling pathways.

All applications are limited to non-clinical research environments.

Scientific References

Peer-reviewed literature data.

Imai S, et al. (Imai S, et al.).“NAD+ and sirtuins.”Nature
Verdin E. (Verdin E.).“NAD+ in aging and disease.”Science
Yoshino J, et al. (Yoshino J, et al.).“NAD+ biosynthesis and metabolic function.”Cell Metabolism
Gerdts J, et al. (Gerdts J, et al.).“SARM1 and NAD+ depletion in axons.”Neuron

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NAD+ Buffered

Research Use Only

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Scientific Context & Applications

Research Profile Access

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