Glutathione

CAS: 70-18-8

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SKU:Glutathione

Glutathione is a laboratory-grade tripeptide investigated in controlled research environments for its role in cellular redox regulation, antioxidant defense signaling, and detoxification-associated metabolic pathways.

Current Lot ID
2602-C121-1500-001
Third-party analytical validation via HPLC & MS / Sequence matching verified

Research Use Only

This product is intended for research purposes only.

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Technical Specification

Scientific Context & Applications

Research Profile Access

View extended technical data, molecular targets, signaling pathways, and historical research timelines for Glutathione

Scientific Context
Molecular classification and background.

Overview of molecular classification and research background. Glutathione (γ-glutamyl-cysteinyl-glycine) is an endogenous tripeptide that functions as a primary intracellular redox buffer. In laboratory research models, glutathione has been characterized for its ability to regulate oxidative signaling pathways and maintain protein thiol homeostasis. Experimental investigations have examined glutathione for its involvement in:
  • Reactive oxygen species (ROS) neutralization
  •  Redox-sensitive signaling pathway modulation
  •  Glutathione peroxidase and transferase–mediated detoxification
  •  Ferroptosis-associated lipid peroxidation regulation
All observations are derived from controlled non-clinical experimental systems and interpreted strictly at the molecular and cellular research level.

Laboratory Applications
Experimental models and settings.

Experimental models and investigational settings.
  • Oxidative Stress Assays: Utilized to assess intracellular redox balance via GSH/GSSG ratios.
  • Detoxification Research: Applied in hepatocyte models examining xenobiotic conjugation pathways.
  • Ferroptosis Models: Investigated in studies evaluating lipid peroxidation-dependent cell death mechanisms.
  • Immune Cell Research: Used in in-vitro systems studying redox-dependent lymphocyte activation signaling.
All applications are limited to non-clinical research environments.

Scientific References
Peer-reviewed literature data.

  • Wu G, et al. (Wu G, et al.).“Glutathione metabolism.”Journal of Nutrition
  • Pompella A, et al. (Pompella A, et al.).“Glutathione functions.”Biochemical Pharmacology
  • Townsend DM, et al. (Townsend DM, et al.).“Glutathione S-transferase structure.”Biomedicine & Pharmacotherapy
  • Dixon SJ, et al. (Dixon SJ, et al.).“Ferroptosis and glutathione.”Cell

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