All Categories, Regenerative & Tissue Research

GHK-Cu

CAS: 49557-75-7

SKU:GHK-Cu

GHK-Cu is a naturally occurring copper-complexed tripeptide investigated in laboratory research for its role in extracellular matrix signaling, gene-expression modulation, and tissue-remodeling pathways in controlled experimental models.

Current Lot ID

2602-C110-10-001

Third-party analytical validation via HPLC & MS / Sequence matching verified

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This product is intended for research purposes only.

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Scientific Context & Applications

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View extended technical data, molecular targets, signaling pathways, and historical research timelines for GHK-Cu

Scientific Context

Molecular classification and background.

GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring tripeptide that functions as a copper-transporting signal molecule in biological systems. In laboratory research models, GHK-Cu has been characterized for its ability to influence transcriptional activity related to extracellular matrix organization and cellular repair signaling. Research investigations have examined GHK-Cu for its involvement in:

Regulation of collagen- and elastin-associated gene expression
Modulation of matrix metalloproteinases (MMPs) and tissue inhibitors (TIMPs)
Copper-dependent cellular signaling mechanisms
Fibrotic and anti-fibrotic pathway balance within connective tissue models

All observations are derived from controlled non-clinical experimental systems and interpreted strictly at the molecular and cellular research level.

Laboratory Applications

Experimental models and settings.

Experimental models and investigational settings.

Fibroblast Culture Studies: Utilized in dermal fibroblast models to examine extracellular matrix protein synthesis signaling.
Tissue Remodeling Research: Applied in laboratory systems evaluating collagen organization and matrix turnover dynamics.
Cellular Aging Models: Investigated for effects on gene-expression patterns associated with cellular senescence.
Cancer-Related Signaling Studies: Used in in-vitro systems examining peptide-mediated modulation of metastatic gene expression.

All applications are limited to non-clinical research environments.

Scientific References

Peer-reviewed literature data.

Pickart L. (Pickart L.).“The human tri-peptide GHK and tissue remodeling.”Journal of Biomaterials Science
Borkow G. (Borkow G.).“Copper peptides and skin.”Current Chemical Biology
Maquart FX, et al. (Maquart FX, et al.).“Stimulation of collagen synthesis.”FEBS Letters
Hong Y, et al. (Hong Y, et al.).“GHK-Cu and metastatic gene expression.”Biochemical Pharmacology

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GHK-Cu

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